Condition Overview

Spasticity is a condition in which certain muscles are continuously contracted, resulting in stiffness that can interfere with normal movement, speech and the ability to walk. It is usually caused by damage to the portion of the brain or spinal cord that controls voluntary movement.

Spasticity is most typical of cerebral palsy and multiple sclerosis, but can also afflict patients with other conditions that affect the nervous system, such as traumatic brain injury, spinal cord injury, stroke and ALS.

When muscles are contracted continuously, it leads to pain and muscle spasms. Deformities of the muscle and joint are also possible. And the powerful drugs often prescribed to treat spasticity may lead to other complications.


Whole plant cannabis extracts in the treatment of spasticity in multiple sclerosis: a systematic review

A preliminary controlled study to determine whether whole-plant cannabis extracts can improve intractable neurogenic symptoms

A tale of two cannabinoids: The therapeutic rationale for combining tetrahydrocannabinol and cannabidiol

THC and CBD oromucosal spray in the management of spasticity associated with multiple sclerosis

Interesting Fact

Spasticity affects more than 12 million people worldwide. That number includes about 80 percent of cerebral palsy and multiple sclerosis patients.