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CANNABINOIDS

What Are Cannabinoids?

One of the most valuable words in the medical marijuana glossary, that all patients need to understand, is cannabinoid. Cannabinoids, like THC, CBD and CBG, are organic chemical compounds that, with terpenes, make up the building blocks of the marijuana plant. Translating into medicinally valuable relief, cannabinoids have been successfully used in the treatment of conditions such as cancer, seizures, and Parkinson’s disease and symptoms such as inflammation, pain and nausea.

Cannabinoids in marijuana provide such medical efficacy to humans because they mimic our own naturally produced endocannabinoids, and bind to the same receptors, located throughout the brain and body. The human endocannabinoid system is responsible for regulating many different body systems, including pain, memory, mood and appetite. The unique ability of cannabinoids in marijuana to be able to communicate with the human body in the same manner that it communicates with itself makes it an ideal medicine for humans.

The following sections provide additional information on some of the more well-known and widely referenced cannabinoids – we’ll help explain what these cannabinoids do and how they may affect the body. We hope that you find this information helpful.

THC

Tetrahydrocannabinol, or THC, is the most well-known and most often the most prevalent cannabinoid found in marijuana. This is the psychoactive component known to produce euphoria, which is more often described as the feeling of being “high.” THC binds primarily to the receptors found throughout the brain.

Research has shown THC to work to reduce or even eliminate pain, nausea and stress while also helping to stimulate the appetite and combat insomnia. In high doses, THC may cause some patients to feel paranoia or an increased heart rate, but those adverse effects will subside with time.

CBD

Cannabidiol, or CBD, is the non-psychoactive cannabinoid famed for significantly reducing symptoms in patients suffering from seizure and spasm disorders such as epilepsy and multiple sclerosis. CBD is the cannabinoid most often recommended for children, elderly and other patients who must remain clear-headed in their activities because it is non-psychoactive, meaning it will not produce euphoria or the feeling of being “high.”

CBD reacts with cannabinoid receptors throughout the human body, and works to relieve inflammation and pain while producing a calming-effect in patients. For this reason, it is often used to treat anxiety and sleep disorders. It has also been shown to work with THC to reduce the size of tumors.

Cannabinol, or CBN, is a mildly psychoactive component found in marijuana which, like strongly psychoactive THC, is derived from tetrahydrocannabinolic acid (THC-A). CBN is created when THC-A oxidizes. CBN can be used effectively as a sleep aid or sedative. This cannabinoid has also been shown to help regulate the immune system, and works to relieve the pain and inflammation caused by several conditions, including arthritis and Crohn’s disease. Studies show that it can be used to reduce the intraocular eye pressure caused by glaucoma. CBN acts as an anti-convulsant, so it is also beneficial to patients suffering from seizure disorders including epilepsy.

CBN

Tetrahydrocannabinolic acid (THCA) is the most abundant non-psychoactive cannabinoid found in marijuana. The health benefits provided by THCA are most well absorbed by the body through a raw method of consumption such as marijuana juicing. THCA works to relieve inflammation and pain, and is an ideal cannabinoid for treating symptoms of such conditions as arthritis, seizures. THCA is an effective neuroprotectant, so it is beneficial in the treatment of such conditions as multiple sclerosis, Alzheimer’s and Parkinson’s disease. It can also help to stimulate the appetite in patients suffering from cachexia and anorexia nervosa. Most impressively, research shows that THC-A helps to slow the proliferation of cancerous cells.

THCA

CBN

Cannabinol, or CBN, is a mildly psychoactive component found in marijuana which, like strongly psychoactive THC, is derived from tetrahydrocannabinolic acid (THC-A). CBN is created when THC-A oxidizes. CBN can be used effectively as a sleep aid or sedative. This cannabinoid has also been shown to help regulate the immune system, and works to relieve the pain and inflammation caused by several conditions, including arthritis and Crohn’s disease. Studies show that it can be used to reduce the intraocular eye pressure caused by glaucoma. CBN acts as an anti-convulsant, so it is also beneficial to patients suffering from seizure disorders including epilepsy.

THCA

Tetrahydrocannabinolic acid (THCA) is the most abundant non-psychoactive cannabinoid found in marijuana. The health benefits provided by THCA are most well absorbed by the body through a raw method of consumption such as marijuana juicing. THCA works to relieve inflammation and pain, and is an ideal cannabinoid for treating symptoms of such conditions as arthritis, seizures. THCA is an effective neuroprotectant, so it is beneficial in the treatment of such conditions as multiple sclerosis, Alzheimer’s and Parkinson’s disease. It can also help to stimulate the appetite in patients suffering from cachexia and anorexia nervosa. Most impressively, research shows that THC-A helps to slow the proliferation of cancerous cells.

THCV

Tetrahydrocannabivarin, or THCV, is a psychoactive cannabinoid found most prevalently in sativa strains of marijuana. It is known to produce a more motivated, alert and energizing feeling of euphoria. For this reason, it is often recommended for daytime or any time when functionality is important. THCV relieves stress, and research shows it can help to reduce or even prevent anxiety and panic attacks. For this reason it plays an important role in the treatment of post-traumatic-stress-disorder (PTSD).

It is also neuroprotective, so it is ideal for treating conditions such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. Unlike THC, THCV works to suppress the appetite, so it is not recommended for patients suffering from cachexia or anorexia nervosa.

CBC

Cannabichromene, or CBC, is a powerful, non-psychoactive cannabinoid, meaning it will not cause a patient to feel “high.” CBC, like THC and CBD, has been shown to encourage the human brain to grow by increasing the viability of developing brain cells in a process known as neurogenesis. CBC plays a significant role in the anti-cancer and anti-tumor capabilities of marijuana.

CBC battles inflammation, as well, but without activating any of the endocannabinoid receptors in the body. For this reason, the healing powers of CBC increase significantly when combined with other cannabinoids, like THC or CBD, which do activate endocannabinoid receptors in the brain and throughout the body.

Cannabigerol, or CBG, is a non-psychoactive cannabinoid typically most abundant in low-THC, high-CBD marijuana strains, including hemp. Like THC, CBG reacts with the cannabinoid receptors in the brain. CBG, however, acts as a buffer to the psychoactivity of THC, by working to alleviate the paranoia sometimes caused by higher levels of THC.

CBG works to fight inflammation, pain and nausea, and works to slow the proliferation of cancer cells. Research has shown it also significantly reduces intraocular eye pressure caused by glaucoma. Strains high in CBG will be beneficial treating conditions such as inflammatory bowel disease, Crohn’s disease and cancer.

CBG

Cannabidivarin (CBDV) is a non-psychoactive cannabinoid that will not cause the euphoric feeling of being “high.” It is found more prevalently in indica strains, specifically landrace indica strains, and strains that are lower in tetrahydrocannabinol (THC).

Like CBD, CBDV significantly reduces the frequency and severity of seizures. It also reduces or even eliminates the nausea associated with several conditions, and helps to reduce inflammation throughout the body. CBDV is also beneficial in the treatment of pain and mood disorders.

CBDV

CBG

Cannabigerol, or CBG, is a non-psychoactive cannabinoid typically most abundant in low-THC, high-CBD marijuana strains, including hemp. Like THC, CBG reacts with the cannabinoid receptors in the brain. CBG, however, acts as a buffer to the psychoactivity of THC, by working to alleviate the paranoia sometimes caused by higher levels of THC.

CBG works to fight inflammation, pain and nausea, and works to slow the proliferation of cancer cells. Research has shown it also significantly reduces intraocular eye pressure caused by glaucoma. Strains high in CBG will be beneficial treating conditions such as inflammatory bowel disease, Crohn’s disease and cancer.

CBDV

Cannabidivarin (CBDV) is a non-psychoactive cannabinoid that will not cause the euphoric feeling of being “high.” It is found more prevalently in indica strains, specifically landrace indica strains, and strains that are lower in tetrahydrocannabinol (THC).

Like CBD, CBDV significantly reduces the frequency and severity of seizures. It also reduces or even eliminates the nausea associated with several conditions, and helps to reduce inflammation throughout the body. CBDV is also beneficial in the treatment of pain and mood disorders.